Aline Dantas

Title: Dr

First name: Aline

Surname: Dantas

Web Site:


Aline Dantas received her PhD in Chemical Biology in 2005 with Prof. Herbert Waldmann at the Max-Planck Institute for Molecular Physiology in Germany. She then moved to Australia where she worked as a postdoc in the labs of Profs Paul Alewood and David Fairlie. She is now a senior peptide chemist at the Institute for Molecular Bioscience in Brisbane, engaged in improving the pharmacological properties of peptide drugs with applications in diabetes, cancer and analgesics. Her research career has been dedicated in developing innovative peptide and protein chemistry (synthesis, structure, function and druggability) with applications in medicine and biotechnology.



Aline Dantas de Araujo, Caspar Christensen, Jens Buchardt, Stephen B. H. Kent, Paul F. Alewood, “Synthesis of a tripeptide mimetic based on dihydroquinolinone and benzoxazinone scaffolds”, Chemistry - an European Journal, 2011, 17, 13983-13986.

Aline Dantas de Araujo, Brid Callaghan, Simon T. Nevin, Norelle L. Day, David J. Craik, Melissa Moretta, Gene Hopping, Macdonald J. Christie, David J. Adams, Paul F. Alewood, “Total synthesis of analgesic conotoxin MrVIB via selenocysteine-assisted folding”, Angewandte Chemie International Edition, 2011, 50, 6527-6529.

Markus Muttenthaler, Asa Anderson, Aline Dantas de Araujo, Zoltan Dekan, Richard J. Lewis, Paul F. Alewood; “Modulating oxytocin activity and plasma stability by disulfide bond engineering”, Journal of Medicinal Chemistry, 2010, 53, 8585-8596.

Markus Muttenthaler, Yesica G. Ramos, Debbie Feytens, Aline Dantas de Araujo, Paul F. Alewood: “p-Nitrobenzyl protection for cysteine and selenocysteine: a more stable alternative to the acetomidomethyl group”, Biopolymers, 2010, 94, 423-432.

Mehdi Mobli, Aline Dantas de Araújo, Lynette K. Lambert, Gregory K. Pierens, Monique J. Windley, Graham M. Nicholson, Paul F. Alewood, Glenn F. King; “Direct Visualization of Disulfide Bonds through Diselenide Proxies Using 77Se NMR Spectroscopy”, Angewandte Chemie International Edition, 2009, 49, 9312-9314; Angewandte Chemie, 2009, 121, 9476-9478.

Aline Dantas de Araújo, Jose M. Palomo, Janine Cramer, Oliver Seitz, Kirill Alexandrov and Herbert Waldmann; “Diels-Alder Ligation of Peptides and Proteins”, Chemistry – an European Journal, 2006, 12, 6095-6109.

Aline Dantas de Araujo, Jose M. Palomo, Janina Cramer, Maja Kohn, Hendrik Schroder, Ron Wacker, Christof Niemeyer, Kirill Alexandrov, Herbert Waldmann, “Diels-Alder Ligation and Surface Immobilization of Proteins”, Angewandte Chemie International Edition, 2006, 45, 296-301; Angewandte Chemie, 2005, 118, 302-307.

Aline Dantas de Araújo, “Diels-Alder Ligation of Peptides and Proteins”, PhD thesis, Dortmund Universität, 2005.

Aline Dantas de Araújo, "Estudos da Redução de Isoxazolinas como Rota Sintética de b-Hidroxicarbonilas" Diplom dissertation, Universidade Federal de Pernambuco, 2000.

Aline Dantas de Araújo, Edmond Bacher, F. W. Joachim Demnitz and Douglas A. Santos; “A Mild Method for the Preparation of 8-Substituted Xanthines from 5,6-Diaminouracils”, Heterocycles, 1999, 51, 29-36.

Former Group Members