Press Links

2021

 

Professor Fairlie was again listed as a highly cited researcher on the Web of Science. Full list:

 recognition.webofscience.com/awards/highly-cited/2021/  


Hoang HN, Hill TA, Fairlie DP. Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability.

Angew Chem Int Edit 2021, 60, 8385-8390. IF 15.3

Poster CASB symposium

https://mobile.twitter.com/HuyNgocHoang1/status/1333961351094419457


López-García P, de Araujo AD, Bergues-Pupo AE, Tunn I, Fairlie DP*, Blank KG*. Fortified coiled coils: enhancing mechanical stability with lactam or metal staples.

Angew Chem Int Edit 2021, 60, 232-236. IF 15.3

https://mobile.twitter.com/angew_chem/status/1321845055490064384


Chen K-E, Guo Q, Hill TA, Cui Y, Kendall AK, Yang Z, Hall RJ, Healy MD, Sacharz J, Norwood SJ, Fonseka S, Xie B, Reid RC, Leneva N, Parton RG, Ghai R, Stroud DA, Fairlie DP, Suga H, Jackson LP, Teasdale RD, Passioura T, Collins BM. De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the retromer endosomal trafficking complex.

Sci Adv 2021, 7, eabg4007.  IF 14.1

https://mobile.twitter.com/brettcollins100/status/1335060691800051713

https://twitter.com/MartinStoermer/status/1466562435721019392?s=20


Jiang Y, Lim J, Wu KC, Xu W, Suen JY, Fairlie DP. PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR.

Br J Pharmacol 2021, 178, 913-932. IF 8.7


Mak JYW, Wu KC, Gupta PK, Barbero S, McLaughlin MG, Lucke AJ, Tng J, Lim J, Loh Z, Sweet MJ, Reid RC, Liu L, Fairlie DP. HDAC7 inhibition by phenacetyl and phenylbenzoyl hydroxamates.

J Med Chem 2021, 64, 2186-2204.  IF 7.4

https://mobile.twitter.com/MartinStoermer/status/1360026724906397698


Duszyc K, Gomez GA, Lagendijk AK, Yau MK, Nanavati BN, Gliddon BL, Hall TE, Verma S, Hogan BM, Pitson SM, Fairlie DP, Parton RG, Yap AS. Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion. 

Curr Biol 2021, 31, 1326-1336.e5. IF 10.8

https://mobile.twitter.com/SmallGTPases/status/1360986719340920833


de Araujo AD, Nguyen HT, Fairlie DP. Late-stage hydrocarbon conjugation and cyclization in synthetic peptides and proteins.

ChemBioChem 2021, 22, 1784-1789. IF 3.2 

Poster Australian peptide Conference 2019   

http://peptides-2019.m.asnevents.com.au/schedule/session/15367/abstract/65962

https://twitter.com/FairlieGroup/status/1399510668663918592?s=20 


2020   

Brayden DJ, Hill TA, Fairlie DP, Maher S, Mrsny RJ. Systemic Delivery of Peptides by the Oral Route: Formulation and medicinal chemistry approaches.

Adv Drug Deliv Rev 2020, 157, 2-36. IF 15.5 ISI Highly Cited

https://mobile.twitter.com/JCRnEDITORS/status/1306529689406595072

https://mobile.twitter.com/search?q=Systemic%20Delivery%20of%20Peptides%20by%20the%20Oral%20Route%3A%20Formulation%20and%20medicinal%20chemistry%20approaches.&src=typed_query


Rowley JA, Reid RC, Poon EKY, Wu KC, Lim J, Lohman RJ, Hamidon JK, Yau MK, Greenup MA, Nielsen DS, Durek T, Iyer A, Fairlie DP. Potent thiophene antagonists of human complement C3a receptor with anti-inflammatory activity.

J Med Chem 2020, 63, 529-541. IF 7.4

https://mobile.twitter.com/FairlieGroup/status/1223115283373547521


Nielsen DS, Lohman RJ, Hoang HN, Fairlie DP, Hill TA. High cell permeability does not predict oral bioavailability for analogues of cyclic heptapeptide sanguinamide A.

Aust J Chem 2020, 73, 344-351. IF 1.3 

Invited Paper

https://mobile.twitter.com/HuyNgocHoang1/status/1232101806395678720


2019 

Malde AK, Hill TA, Iyer A, Fairlie DP. Crystal Structures of Protein-Bound Cyclic Peptides.

Chemical Reviews 2019, 119, 9861-9914. IF 60.6

https://mobile.twitter.com/FairlieGroup/status/1172296389109223425


Hoang HN, Wu C, Hill TA, de Araujo AD, Berhnhardt PV, Liu L, Fairlie DP. A long-range n to pi* interaction secures the smallest known a-helix in water.

Angew Chem Int Edit 2019, 58, 18873-18877. IF 15.3

Chemistry in Australia March/April 2020 p10 

Chongyang- Talk at IMB research days October 2019

https://mobile.twitter.com/angew_chem/status/1193023329596321794

https://chemaust.raci.org.au/sites/default/files/pdf/2020/CiA_Mar%3AApr%202020.pdf

https://twitter.com/HuyNgocHoang1/status/1235000382419394563?s=20

https://twitter.com/HuyNgocHoang1/status/1222405323614343168?s=20


Hoang HN, Hill TA, Ruiz-Gómez G, Diness F, Mason JM, Wu C, Abbenante G,  Shepherd NE, Fairlie DP. Twists or Turns: stabilizing alpha versus beta turns in tetrapeptides.

Chem Sci 2019, 10, 10595-10600. IF 9.8

Poster CASB symposium 2019

https://twitter.com/HuyNgocHoang1/status/1196202122343137283?s=20


Lohman RJ, Nielsen DS, Kok WM, Hoang HN, Hill T, Fairlie DP. Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities.

Chem Commun 2019, 55, 13362-13365. IF 6.2

Poster CASB symposium 2019


 
2018  

de Araujo AD, Lim J, Wu K-C, Xiang Y, Good AC, Skerlj R, Fairlie DP. Bicyclic helical peptides as dual inhibitors selective for Bcl2A1 and Mcl-1 proteins. 

J Med Chem 2018, 61, 2962-2972. 

Poster Australian peptide Conference 2019  

http://peptides-2019.m.asnevents.com.au/schedule/session/15353/abstract/66008


Perry SR, Hill TA, de Araujo AD, Hoang HN, Fairlie DP. Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability.

Org Biomol Chem 2018, 16, 367-371.

Poster RACI Medicinal Chemistry Conference Brisbane 18th -21st November 2018